Comparing Antigenicity and Immunogenicity of Engineered gp120
نویسندگان
چکیده
منابع مشابه
Comparing antigenicity and immunogenicity of engineered gp120.
We have engineered monomeric gp120 in such a way as to favorably present the conserved epitope for the broadly neutralizing antibody b12 while lowering the exposure of epitopes recognized by some weakly neutralizing and nonneutralizing antibodies. The work presented here describes the immune response in rabbits immunized with two prototype, engineered gp120s to explore the relationship between ...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2005
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.79.19.12148-12163.2005